Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19417683 | 0.84 | PTK2 (0.36) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL13881366 | 0.82 | PTK2 (0.35) | MEN1KMT2AALDH1A1NPC1KDM4E | |
| SCHEMBL10680241 | 0.81 | ALDH1A1 (0.48) | KMT2AALDH1A1SMN1; SMN2NPC1KDM4E | |
| SCHEMBL11093773 | 0.79 | NPSR1 (0.35) | MEN1KMT2AALDH1A1NPC1KDM4E | |
| SCHEMBL10675581 | 0.77 | KMT2A (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL10681391 | 0.74 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2NPC1KDM4EEGFR | |
| SCHEMBL10508336 | 0.74 | CA1 (0.46) | MEN1KMT2AALDH1A1NPC1KDM4E | |
| SCHEMBL10734373 | 0.73 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2NPC1KDM4ETP53 | |
| SCHEMBL20247452 | 0.73 | GAA (0.33) | POLB | |
| SCHEMBL5276681 | 0.72 | GLA (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4776878-A | PLANT GROWTH REGULATORS OR HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-10-11 | — | — | US | disclosed |
| US-4544401-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-10-01 | — | — | US | disclosed |
| EP-0013480-A2 | Herbicidal pyridinesulfonamides, preparation and use thereof and compositions containing them | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-07-23 | — | — | EP | disclosed |