SCHEMBL10508336

SCHEMBL10508336

COC(=O)c1ccccc1S(=O)(=O)N(C)C(=O)Nc1nc(OC)nc(OC)n1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA5A P35218 1/20 0.46
CA9 Q16790 1/20 0.46
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
GAA P10253 2/20 0.40
NPC1 O15118 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
SLC40A1 Q9NP59 1/20 0.39
KDM4E B2RXH2 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
MAPT P10636 1/20 0.38
ALDH1A1 P00352 1/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
HSD17B10 Q99714 1/20 0.37
POLB P06746 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10949326 0.82 TSHR (0.46) KMT2AMEN1GAAL3MBTL1KDM4E
SCHEMBL19417683 0.81 PTK2 (0.36) KMT2AMEN1GAANPC1KDM4E
SCHEMBL7934335 0.80 F2 (0.40) CA1CA2CA5ACA9KMT2A
SCHEMBL10693785 0.80 GSTO1 (0.41) KMT2AMEN1SLC40A1MAPTPOLB
SCHEMBL13881366 0.79 PTK2 (0.35) KMT2AMEN1GAANPC1KDM4E
SCHEMBL7023958 0.79 NPC1 (0.50) CA1CA2CA5ACA9KMT2A
SCHEMBL11202823 0.77 CA1 (0.46) CA1CA2CA5ACA9KMT2A
SCHEMBL10948891 0.76 TSHR (0.43) KMT2AGAAL3MBTL1KDM4ENPSR1
SCHEMBL11067484 0.76 TSHR (0.47) KMT2AMEN1GAAL3MBTL1MAPT
SCHEMBL11182357 0.76 CA1 (0.42) CA1CA2CA5ACA9KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4830662-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-05-16 US disclosed
US-4818278-A N-/HETEROCYCLICAMINOCARBONYL/ARYL SULFONAMIDES; HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-04-04 US disclosed
US-4755216-A Herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-07-05 US disclosed
US-4721520-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-01-26 US disclosed
US-4689072-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-08-25 US disclosed
US-4687507-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-08-18 US disclosed
US-4647303-A Agriculture sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-03-03 US disclosed
US-4627873-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-12-09 US disclosed
US-4592978-A Herbicides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-06-03 US disclosed
US-4591378-A Agricultural sulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-05-27 US disclosed
US-4564384-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-01-14 US disclosed
US-4545808-A PREEMERGENCE AND POSTEMERGENCE HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-10-08 US disclosed
US-4536576-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-08-20 US disclosed
US-4394506-A HERBICIDWS, PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-19 US disclosed
US-4383113-A PLANT GROWTH REGULATORS, HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1983-05-10 US disclosed
EP-0007687-B1 SULFONAMIDES, PROCESSES FOR THEIR PREPARATION, COMPOSITIONS CONTAINING SAID SULFONAMIDES AND A METHOD FOR CONTROLLING THE GROWTH OF VEGETATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-03-30 EP disclosed
EP-0007687-A1 Sulfonamides, processes for their preparation, compositions containing said sulfonamides and a method for controlling the growth of vegetation E.I. DU PONT DE NEMOURS AND COMPANY (US) 1980-02-06 EP disclosed