Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 4/20 | 0.50 |
| ▸ | CMA1 | P23946 | 2/20 | 0.50 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.49 |
| ▸ | TDP2 | O95551 | 2/20 | 0.48 |
| ▸ | KIF11 | P52732 | 5/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3224720 | 0.83 | TDP2 (0.66) | AHRCMA1EIF2AK2TDP2KIF11 | |
| SCHEMBL6125101 | 0.77 | AHR (0.56) | AHRCMA1EIF2AK2TDP2KIF11 | |
| SCHEMBL11242330 | 0.74 | MAOB (0.58) | KIF11NR1H2NR1H3PGR | |
| SCHEMBL10060231 | 0.72 | AHR (0.50) | AHRCMA1EIF2AK2TDP2KIF11 | |
| SCHEMBL11367671 | 0.72 | KIF11 (0.52) | KIF11NR1H2NR1H3 | |
| SCHEMBL11243199 | 0.72 | HDAC1 (0.45) | KIF11NR1H2NR1H3PGR | |
| SCHEMBL260027 | 0.71 | AHR (0.61) | AHRCMA1EIF2AK2TDP2CRBN | |
| SCHEMBL31478025 | 0.71 | AHR (0.61) | AHRCMA1EIF2AK2TDP2CRBN | |
| SCHEMBL30648196 | 0.71 | AHR (0.61) | AHRCMA1EIF2AK2TDP2CRBN | |
| SCHEMBL1833499 | 0.71 | AHR (0.61) | AHRCMA1EIF2AK2TDP2CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4727180-A | SIDE EFFECT REDUCTION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-02-23 | — | — | US | disclosed |