Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.69 |
| ▸ | KMO | O15229 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685864 | 0.86 | MRGPRX4 (0.51) | MRGPRX4PTGER4PTGER2MEN1MAPT | |
| SCHEMBL10668436 | 0.82 | MRGPRX4 (1.00) | MRGPRX4KMOAKR1C3MEN1MAPT | |
| SCHEMBL31568461 | 0.82 | MRGPRX4 (1.00) | MRGPRX4KMOAKR1C3MEN1MAPT | |
| SCHEMBL29103540 | 0.80 | MRGPRX4 (0.74) | MRGPRX4KMOAKR1C3MAPTKMT2A | |
| SCHEMBL30740807 | 0.80 | MRGPRX4 (0.74) | MRGPRX4KMOAKR1C3MAPTKMT2A | |
| SCHEMBL10674162 | 0.80 | MRGPRX4 (0.74) | MRGPRX4KMOAKR1C3MEN1MAPT | |
| SCHEMBL3791436 | 0.79 | MRGPRX4 (0.69) | MRGPRX4KMOAKR1C3MEN1KMT2A | |
| SCHEMBL30278570 | 0.79 | MRGPRX4 (0.69) | MRGPRX4KMOAKR1C3MEN1KMT2A | |
| SCHEMBL11151654 | 0.79 | MRGPRX4 (0.73) | MRGPRX4KMOAKR1C3MEN1KMT2A | |
| SCHEMBL22480945 | 0.79 | MRGPRX4 (0.76) | MRGPRX4MEN1MAPTKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4743703-A | Herbicidal 4-fluoroalkyl-4'-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1988-05-10 | — | — | US | disclosed |