Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.68 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.66 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.66 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.62 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.61 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.61 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.61 |
| ▸ | LDHA | P00338 | 1/20 | 0.61 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.61 |
| ▸ | SRC | P12931 | 1/20 | 0.61 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.61 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.61 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.61 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.61 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8388000 | 0.93 | FBP1 (0.64) | FBP1SIRT2SIRT1ENTPD1DNPH1 | |
| SCHEMBL20266254 | 0.92 | FBP1 (0.63) | FBP1SIRT2SIRT1ENTPD1DNPH1 | |
| Adenosine Phosphate SCHEMBL31666008 | 0.88 | P2RY1 (0.69) | FBP1DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL4206199 | 0.87 | ENTPD1 (0.67) | FBP1ENTPD1TRPM2 | |
| SCHEMBL10528520 | 0.87 | SIRT2 (0.75) | FBP1SIRT2SIRT1ENTPD1DNPH1 | |
| SCHEMBL4209829 | 0.86 | ENTPD1 (0.66) | FBP1ENTPD1TRPM2 | |
| SCHEMBL2317501 | 0.85 | FBP1 (0.54) | FBP1 | |
| SCHEMBL2318704 | 0.85 | FBP1 (0.56) | FBP1SIRT2SIRT1ENTPD1 | |
| Adenosine Phosphate SCHEMBL20529828 | 0.85 | P2RY1 (0.65) | FBP1DNPH1PRKAB2TRPM2LDHA | |
| SCHEMBL31685855 | 0.85 | SIRT2 (0.75) | FBP1SIRT2SIRT1ENTPD1DNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4791055-A | ENZYME-CLEAVABLE BONDS | MILES INC. (US) | 1988-12-13 | — | — | US | disclosed |
| US-4629688-A | CLINICAL ANALYSIS | MILES LABORATORIES, INC. (US) | 1986-12-16 | — | — | US | disclosed |
| US-4383031-A | LIGANDS; IMMUNOASSAY; SIMPLIFICATION; DIAGNOSIS/MEDICAL/ | MILES LABORATORIES, INC. (US) | 1983-05-10 | — | — | US | disclosed |