Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682913 | 0.81 | SRD5A1 (0.38) | POLBHSD17B10ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL31356860 | 0.81 | MAPT (0.50) | POLBHSD17B10ALDH1A1SMN1; SMN2ALOX12 | |
| SCHEMBL31356794 | 0.77 | POLB (0.70) | POLBHSD17B10ALDH1A1SMN1; SMN2ALOX12 | |
| SCHEMBL10682369 | 0.76 | MAPT (0.48) | POLBHSD17B10ALDH1A1SMN1; SMN2ALOX12 | |
| SCHEMBL15455058 | 0.76 | POLB (0.68) | POLBHSD17B10ALDH1A1SMN1; SMN2ALOX12 | |
| SCHEMBL31356720 | 0.75 | POLB (0.54) | POLBHSD17B10ALDH1A1SMN1; SMN2ALOX12 | |
| SCHEMBL7560192 | 0.75 | TP53 (0.44) | POLBHSD17B10ALDH1A1MAPTTDP1 | |
| SCHEMBL16956272 | 0.69 | DRD2 (0.47) | POLBHSD17B10ALDH1A1TDP1DRD2 | |
| SCHEMBL10679929 | 0.69 | POLB (0.50) | POLBHSD17B10ALDH1A1SMN1; SMN2ALOX12 | |
| SCHEMBL10922428 | 0.69 | MAPT (0.55) | POLBHSD17B10ALDH1A1SMN1; SMN2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4760192-A | Herbicidal cyclohexane-1,3-dione derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-07-26 | — | — | US | disclosed |
| US-4717418-A | CEREAL SELECTIVE HERBICIDES | ICI AUSTRALIA LIMITED (AU) | 1988-01-05 | — | — | US | disclosed |
| EP-0080301-A2 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1983-06-01 | — | — | EP | disclosed |