Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.56 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.55 |
| ▸ | BAX | Q07812 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | SCN4A | P35499 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3681820 | 1.00 | LTA4H (0.65) | LTA4HTSHRALDH1A1GSTP1NR1H2 | |
| SCHEMBL2856821 | 1.00 | LTA4H (0.65) | LTA4HTSHRALDH1A1GSTP1NR1H2 | |
| SCHEMBL28439743 | 0.97 | LTA4H (0.61) | LTA4HTSHRALDH1A1GSTP1NR1H2 | |
| SCHEMBL21921128 | 0.97 | LTA4H (0.71) | LTA4HTSHRALDH1A1GSTP1NR1H2 | |
| SCHEMBL403667 | 0.97 | LTA4H (0.71) | LTA4HTSHRALDH1A1GSTP1NR1H2 | |
| Biphenyl SCHEMBL10838288 | 0.97 | LTA4H (0.71) | LTA4HTSHRALDH1A1GSTP1NR1H2 | |
| SCHEMBL28436317 | 0.97 | LTA4H (0.61) | LTA4HTSHRALDH1A1GSTP1NR1H2 | |
| SCHEMBL9190364 | 0.97 | LTA4H (0.71) | LTA4HTSHRALDH1A1GSTP1NR1H2 | |
| SCHEMBL28431578 | 0.97 | LTA4H (0.61) | LTA4HTSHRALDH1A1GSTP1NR1H2 | |
| SCHEMBL31588897 | 0.94 | LTA4H (0.67) | LTA4HTSHRALDH1A1GSTP1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4731484-A | Haloacetyl derivatives of aromatic compounds | THE DOW CHEMICAL COMPANY (US) | 1988-03-15 | — | — | US | disclosed |
| EP-0189266-A2 | Purification of haloacetyl derivatives of aromatic hydrocarbons | THE DOW CHEMICAL COMPANY (US) | 1986-07-30 | — | — | EP | disclosed |