Biphenyl

Biphenyl

SCHEMBL10838288

c1ccc(-c2ccccc2)cc1.c1ccc(Oc2ccc(-c3ccc(Oc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 9/20 0.71
TSHR P16473 1/20 0.71
GSTP1 P09211 1/20 0.60
NR1H2 P55055 1/20 0.59
BAX Q07812 1/20 0.59
MAOA P21397 1/20 0.59
ALDH1A1 P00352 1/20 0.53
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
SCN4A P35499 1/20 0.52
MCL1 Q07820 2/20 0.50
TLR8 Q9NR97 1/20 0.50
BCL2L1 Q07817 1/20 0.49
NISCH Q9Y2I1 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21921128 1.00 LTA4H (0.71) LTA4HTSHRGSTP1NR1H2BAX
SCHEMBL403667 1.00 LTA4H (0.71) LTA4HTSHRGSTP1NR1H2BAX
SCHEMBL9190364 1.00 LTA4H (0.71) LTA4HTSHRGSTP1NR1H2BAX
SCHEMBL31588897 0.97 LTA4H (0.67) LTA4HTSHRGSTP1NR1H2BAX
SCHEMBL6406035 0.97 LTA4H (0.75) LTA4HTSHRGSTP1NR1H2BAX
SCHEMBL10686173 0.97 LTA4H (0.65) LTA4HTSHRGSTP1NR1H2BAX
SCHEMBL2856821 0.97 LTA4H (0.65) LTA4HTSHRGSTP1NR1H2BAX
SCHEMBL3681820 0.97 LTA4H (0.65) LTA4HTSHRGSTP1NR1H2BAX
SCHEMBL197414 0.97 LTA4H (0.75) LTA4HTSHRGSTP1NR1H2BAX
SCHEMBL2860844 0.97 LTA4H (0.75) LTA4HTSHRGSTP1NR1H2BAX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4611033-A Process for stabilizing a poly(aryl ether ketone) UNION CARBIDE CORPORATION (US) 1986-09-09 US claimed