Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | F7 | P08709 | 7/20 | 0.43 |
| ▸ | F3 | P13726 | 7/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | PPARD | Q03181 | 5/20 | 0.43 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 3/20 | 0.43 |
| ▸ | FABP4 | P15090 | 3/20 | 0.43 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1083220 | 0.94 | TOP1 (0.47) | ALDH1A1F7F3PPARGPPARD | |
| SCHEMBL11451513 | 0.94 | TOP1 (0.47) | ALDH1A1F7F3PPARGPPARD | |
| SCHEMBL1083217 | 0.94 | TOP1 (0.47) | ALDH1A1F7F3PPARGPPARD | |
| SCHEMBL11573698 | 0.94 | TOP1 (0.47) | ALDH1A1F7F3PPARGPPARD | |
| SCHEMBL17421815 | 0.94 | TOP1 (0.47) | ALDH1A1F7F3PPARGPPARD | |
| SCHEMBL11234405 | 0.94 | TOP1 (0.47) | ALDH1A1F7F3PPARGPPARD | |
| SCHEMBL11216573 | 0.84 | TOP1 (0.35) | TOP1TBXA2R | |
| SCHEMBL11182020 | 0.82 | TOP1 (0.33) | TOP1 | |
| SCHEMBL13655741 | 0.80 | CNR1 (0.36) | ALDH1A1F7F3MAPTHPGD | |
| SCHEMBL11106126 | 0.80 | F13A1 (0.46) | MAPTLMNAPTGS1PTGS2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4737590-A | PROSTAGLANDIN INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1988-04-12 | — | — | US | disclosed |
| US-4439365-A | TRIPHENYLMETHOXY ALKENYLMAGNESIUM HALIDES | AMERICAN CYANAMID COMPANY (US) | 1984-03-27 | — | — | US | disclosed |
| US-4343949-A | PROSTAGLANDIN REARRANGEMENTS | AMERICAN CYANAMID COMPANY (US) | 1982-08-10 | — | — | US | disclosed |
| US-4293704-A | Novel 2-substituted-3,4-epoxycyclopentan-1-ones, 2-substituted-3,4-epoxycyclopentan-1-ols, and various 2-substituted-cyclopentenones | AMERICAN CYANAMID COMPANY (US) | 1981-10-06 | — | — | US | disclosed |
| US-4237316-A | ISOMERIZATION OF PROSTAGLANDIN INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1980-12-02 | — | — | US | disclosed |
| US-4179574-A | PROSTAGLANDIN INTERMEDIATES | AMERICAN CYANAMID COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| US-4123456-A | BRONCHODILATORS, HYPOTENSIVES, ANTIULCER, ANTISECRETORY, MICROBIOCIDES, ANTICONVULSANTS, OXYTOCICS, ANALGESICS, DIURETICS, ANTIINFLAMMATORY, ANTICOAGULANTS | AMERICAN CYANAMID COMPANY (US) | 1978-10-31 | — | — | US | disclosed |
| US-4110368-A | PROSTAGLANDINS, BRONCHODILATOR, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-4060540-A | BRONCHODILATORS, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1977-11-29 | — | — | US | disclosed |
| US-4007210-A | PROSTANOIC ACID DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1977-02-08 | — | — | US | disclosed |
| US-3966773-A | BRONCHODILATOR, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1976-06-29 | — | — | US | disclosed |
| US-3932479-A | BRONCHODILATOR, HYPOTENSIVE, ANTIULCER | AMERICAN CYANAMID COMPANY (US) | 1976-01-13 | — | — | US | disclosed |