Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.43 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10689802 | 0.92 | KDM4E (0.67) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL10689144 | 0.88 | KDM4E (0.68) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL10689137 | 0.88 | KDM4E (0.68) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL10689149 | 0.88 | KDM4E (0.68) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL10375286 | 0.86 | KCNH2 (0.59) | KDM4EHSD17B10ALDH1A1HPGDKCNH2 | |
| SCHEMBL20850987 | 0.83 | KDM4E (0.47) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL9524138 | 0.83 | KDM4E (0.72) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL9070334 | 0.83 | KDM4E (0.69) | KDM4EHSD17B10ALDH1A1HPGDPMP22 | |
| SCHEMBL10690023 | 0.83 | DRD3 (0.64) | KDM4EHSD17B10ALDH1A1HPGDDRD3 | |
| SCHEMBL10621416 | 0.82 | KDM4E (0.68) | KDM4EHSD17B10ALDH1A1HPGDPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4753953-A | Pyridonecarboxylic acid derivatives and antibacterial pharmaceutical compositions thereof | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1988-06-28 | — | — | US | disclosed |
| EP-0208210-A1 | Pyridonecarboxylic acid derivatives and process for their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-01-14 | — | — | EP | disclosed |