Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | BRD4 | O60885 | 1/20 | 0.63 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.54 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688010 | 0.88 | DRD3 (0.67) | DRD3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL10688019 | 0.88 | DRD3 (0.67) | DRD3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL10688024 | 0.88 | DRD3 (0.67) | DRD3ALDH1A1KDM4EHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL10879015 | 0.83 | KDM4E (0.70) | DRD3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL10621421 | 0.83 | TOP1 (0.72) | DRD3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL10686208 | 0.83 | KDM4E (0.66) | DRD3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9749226 | 0.82 | KDM4E (0.71) | DRD3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL10618744 | 0.82 | DRD3 (0.76) | DRD3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL9749538 | 0.81 | DRD3 (0.71) | DRD3ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL10621378 | 0.81 | ALDH1A1 (0.73) | DRD3ALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4753953-A | Pyridonecarboxylic acid derivatives and antibacterial pharmaceutical compositions thereof | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1988-06-28 | — | — | US | disclosed |
| EP-0208210-A1 | Pyridonecarboxylic acid derivatives and process for their preparation | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1987-01-14 | — | — | EP | disclosed |