Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | CFTR | P13569 | 9/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1606455 | 0.91 | NPC1 (0.79) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL11924959 | 0.82 | RAB9A (1.00) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL30136193 | 0.79 | NPC1 (0.60) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL394777 | 0.79 | CFTR (0.65) | RAB9ANPC1CFTRMAOB | |
| SCHEMBL23727897 | 0.79 | NPC1 (0.60) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL399749 | 0.77 | CFTR (0.80) | CFTRMAOB | |
| SCHEMBL398391 | 0.76 | CFTR (1.00) | RAB9ANPC1CFTRMAOB | |
| SCHEMBL13774685 | 0.76 | GLA (1.00) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL396316 | 0.76 | CFTR (0.61) | RAB9AALDH1A1SMN1; SMN2CFTRMAOB | |
| SCHEMBL15113529 | 0.75 | ALDH1A1 (0.75) | RAB9ANPC1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4786644-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-11-22 | — | — | US | claimed |