Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.53 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10659085 | 0.88 | KMT2A (0.64) | MEN1KMT2ARAB9APOLBTP53 | |
| SCHEMBL10660556 | 0.85 | CASP3 (0.50) | MEN1KMT2ARAB9ALMNAMAPK1 | |
| SCHEMBL10656579 | 0.81 | DEGS1 (0.53) | MEN1KMT2ARAB9ARXFP1TP53 | |
| SCHEMBL10689732 | 0.80 | RAB9A (0.47) | MEN1KMT2ARAB9APOLBRXFP1 | |
| SCHEMBL10758439 | 0.80 | GRM5 (0.62) | MEN1KMT2ARAB9ATP53SMN1; SMN2 | |
| SCHEMBL10662590 | 0.77 | RXFP1 (0.61) | MEN1KMT2ARAB9APOLBRXFP1 | |
| SCHEMBL10756522 | 0.77 | KMT2A (0.50) | MEN1KMT2ARAB9APOLBTP53 | |
| SCHEMBL10756465 | 0.77 | RAB9A (0.58) | KMT2ARAB9APOLBRXFP1TP53 | |
| SCHEMBL10758406 | 0.76 | NPC1 (0.59) | MEN1KMT2ARAB9ARXFP1NPC1 | |
| SCHEMBL10688953 | 0.76 | MAOB (0.56) | MEN1KMT2ARAB9APKMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4744812-A | HALOGENATED DIPHENYL ETHER | BASF AKTIENGESELLSCHAFT (DE) | 1988-05-17 | — | — | US | disclosed |
| US-4720500-A | N-1,8-naphthyridin-2-yl amides useful as immunostimulants | RHONE-POULENC SANTE (FR) | 1988-01-19 | — | — | US | disclosed |