Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | IAPP | P10997 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692300 | 0.84 | CYP2C19 (0.58) | HPGDCYP2C19CYP1A2CYP2C9APEX1 | |
| SCHEMBL10692792 | 0.79 | TNKS2 (0.38) | HPGDCYP1A2CYP2C9APEX1ALDH1A1 | |
| SCHEMBL10688054 | 0.76 | CYP1A2 (0.58) | CYP1A2CYP2C9BCHE | |
| SCHEMBL5872997 | 0.74 | CYP2C19 (0.46) | HPGDCYP2C19CYP1A2CYP2C9LMNA | |
| SCHEMBL10689601 | 0.73 | HTT (0.46) | HPGDCYP2C19CYP1A2APEX1LMNA | |
| SCHEMBL5935700 | 0.73 | CYP2C19 (0.72) | HPGDCYP2C19CYP1A2CYP2C9LMNA | |
| SCHEMBL6654287 | 0.72 | TYR (0.43) | CYP1A2CYP2C9THRBMAPTTP53 | |
| SCHEMBL6650280 | 0.72 | TYR (0.43) | CYP1A2CYP2C9THRBMAPTTP53 | |
| SCHEMBL39524 | 0.72 | TYR (0.43) | CYP2C9THRBMAPTTP53 | |
| Dimethylamine SCHEMBL1275482 | 0.71 | HSPA5 (0.44) | HPGDCYP2C19CYP1A2CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4741846-A | STABILIZERS FOR POLYMERS OR LUBRICANTS | CIBA-GEIGY CORPORATION (US) | 1988-05-03 | — | — | US | disclosed |
| EP-0170624-B1 | 2,4,6-TRIFUNCTIONALIZED PHENOLS | CIBA-GEIGY AG (CH) | 1988-01-07 | — | — | EP | disclosed |