SCHEMBL10692300

SCHEMBL10692300

O=C(O)CCSCc1cc(CSCCC(=O)O)c(O)c(CSCCC(=O)O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.58
HPGD P15428 3/20 0.48
LMNA P02545 2/20 0.45
HSD17B10 Q99714 2/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
PTGER1 P34995 1/20 0.39
PTGER4 P35408 1/20 0.39
PTGER3 P43115 1/20 0.39
PTGER2 P43116 1/20 0.39
TSHR P16473 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
EGFR P00533 2/20 0.36
ERBB2 P04626 2/20 0.36
TP53 P04637 3/20 0.35
APEX1 P27695 1/20 0.34
ALDH1A1 P00352 4/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5872997 0.85 CYP2C19 (0.46) CYP2C19HPGDLMNAHSD17B10KMT2A
SCHEMBL10686362 0.84 HPGD (0.40) CYP2C19HPGDLMNACYP1A2CYP2C9
Dimethylamine SCHEMBL1275482 0.82 HSPA5 (0.44) CYP2C19HPGDLMNAKMT2ATSHR
SCHEMBL10689601 0.81 HTT (0.46) CYP2C19HPGDLMNAKMT2ACYP1A2
SCHEMBL14523074 0.80 CYP2C19 (0.44) CYP2C19HPGDLMNAHSD17B10KMT2A
SCHEMBL1275481 0.78 CYP2C19 (0.40) CYP2C19HPGDLMNAHSD17B10KMT2A
SCHEMBL10688054 0.77 CYP1A2 (0.58) TDP1CYP1A2CYP2C9
SCHEMBL9507235 0.77 CYP2C19 (0.51) CYP2C19HPGDLMNAHSD17B10KMT2A
SCHEMBL10692792 0.73 TNKS2 (0.38) HPGDTSHRCYP1A2CYP2C9APEX1
SCHEMBL44801 0.73 CYP2C19 (1.00) CYP2C19HPGDLMNAHSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4741846-A STABILIZERS FOR POLYMERS OR LUBRICANTS CIBA-GEIGY CORPORATION (US) 1988-05-03 US disclosed
EP-0170624-B1 2,4,6-TRIFUNCTIONALIZED PHENOLS CIBA-GEIGY AG (CH) 1988-01-07 EP disclosed