Dimethylamine

Dimethylamine

SCHEMBL1275482

CC(C)(C)c1cc(CSCCC(=O)O)cc(CSCCC(=O)O)c1O.CNC

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.44
CYP2C19 P33261 2/20 0.43
HPGD P15428 1/20 0.41
GAA P10253 6/20 0.40
VCAM1 P19320 4/20 0.39
KMT2A Q03164 3/20 0.38
HIF1A Q16665 2/20 0.36
CYP2C9 P11712 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GLRA3 O75311 1/20 0.36
GLRB P48167 1/20 0.36
MEN1 O00255 2/20 0.35
ALDH1A1 P00352 2/20 0.35
TSHR P16473 2/20 0.35
USP2 O75604 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5872997 0.96 CYP2C19 (0.46) HSPA5CYP2C19HPGDGAAVCAM1
SCHEMBL1275481 0.88 CYP2C19 (0.40) HSPA5CYP2C19HPGDGAAVCAM1
SCHEMBL9507235 0.88 CYP2C19 (0.51) CYP2C19HPGDGAAVCAM1KMT2A
Dimethylamine SCHEMBL1275473 0.87 HSPA5 (0.47) HSPA5CYP2C19GAAVCAM1KMT2A
SCHEMBL4633458 0.82 HSPA5 (0.46) HSPA5CYP2C19GAAVCAM1KMT2A
SCHEMBL10692300 0.82 CYP2C19 (0.58) CYP2C19HPGDKMT2ACYP2C9SMN1; SMN2
SCHEMBL1275496 0.79 HSPA5 (0.49) HSPA5CYP2C19HPGDGAAKMT2A
SCHEMBL1275492 0.79 HSPA5 (0.57) HSPA5CYP2C19HPGDGAAKMT2A
SCHEMBL1275785 0.79 ALDH1A1 (0.41) HSPA5GAAVCAM1KMT2AHIF1A
SCHEMBL1275783 0.79 ALDH1A1 (0.41) HSPA5GAAVCAM1KMT2AHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1848768-B1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEMICAL LTD (KR) 2011-02-09 EP disclosed
US-7452933-B2 Cross-linked polyethylene having excellent inhibition of sweat-out and insulation properties LG CHEM, LTD. (KR) 2008-11-18 US disclosed
EP-1848768-A4 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEMICAL LTD (KR) 2008-06-11 EP disclosed
EP-1848768-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG Chem, Ltd. (KR) 2007-10-31 EP disclosed
WO-2007097511-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEM, LTD. (KR) 2007-08-30 WO disclosed
US-20070203278-A1 CROSS-LINKED POLYETHYLENE HAVING EXCELLENT INHIBITION OF SWEAT-OUT AND INSULATION PROPERTIES LG CHEM, LTD. (KR) 2007-08-30 US disclosed