Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775561 | 0.69 | ALDH1A1 (0.48) | TSHRTP53ALOX15MAPK1HSD17B10 | |
| SCHEMBL576071 | 0.67 | TP53 (0.31) | TSHRTP53ALOX15MAPK1HSD17B10 | |
| SCHEMBL575975 | 0.67 | TP53 (0.31) | TSHRTP53ALOX15MAPK1HSD17B10 | |
| SCHEMBL8437256 | 0.67 | HSD17B10 (0.50) | TSHRTP53ALOX15MAPK1HSD17B10 | |
| SCHEMBL30417485 | 0.65 | TP53 (0.31) | TSHRTP53ALOX15MAPK1HSD17B10 | |
| SCHEMBL2701518 | 0.63 | — | — | |
| SCHEMBL776563 | 0.63 | HPGD (0.30) | TSHRHPGDCASP7 | |
| SCHEMBL5526352 | 0.63 | — | — | |
| Methanethiosulfonic Acid Pentafluorophenylmethyl Ester SCHEMBL7186610 | 0.60 | TRPA1 (0.36) | TSHRHPGDCASP7 | |
| SCHEMBL775858 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745227-A | SULFIDES, AS REVERSE PHOTOCHROMIC DYES IN PLASTICS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1988-05-17 | — | — | US | disclosed |