Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 8/20 | 0.74 |
| ▸ | ATP4B | P51164 | 8/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.74 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.74 |
| ▸ | BLM | P54132 | 1/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1815961 | 0.85 | ATP4A (1.00) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL10689756 | 0.85 | ATP4A (0.55) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| Iodide SCHEMBL10691067 | 0.84 | ATP4A (0.54) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL2192822 | 0.80 | ATP4A (1.00) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL10531597 | 0.77 | ATP4A (0.69) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL10694506 | 0.77 | ATP4A (0.48) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL2192635 | 0.76 | ATP4A (0.83) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL10690155 | 0.76 | ATP4A (0.55) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL10533472 | 0.76 | ATP4A (0.81) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL2189930 | 0.76 | ATP4A (0.81) | ATP4AATP4BMAPK1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738967-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| US-4686227-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-08-11 | — | — | US | disclosed |
| EP-0165545-A2 | Imidazoisoquinoline compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-12-27 | — | — | EP | disclosed |