Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MERTK | Q12866 | 2/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31715931 | 1.00 | VCAM1 (0.59) | VCAM1TDP1TSHRKAT2BMAPT | |
| SCHEMBL203082 | 0.85 | VCAM1 (0.64) | VCAM1TDP1TSHRKAT2BMAPT | |
| SCHEMBL29217568 | 0.83 | TDP1 (0.60) | VCAM1TDP1TSHRMAPTRECQL | |
| SCHEMBL20982786 | 0.82 | MERTK (0.56) | VCAM1TDP1TSHRKAT2BMAPT | |
| SCHEMBL4477143 | 0.82 | VCAM1 (0.70) | VCAM1TDP1TSHRKAT2BMAPT | |
| 2-Nitroaniline SCHEMBL7033834 | 0.82 | VCAM1 (0.55) | VCAM1TDP1TSHRKAT2BMAPT | |
| SCHEMBL4385438 | 0.79 | VCAM1 (0.61) | VCAM1TDP1KAT2BMAPTALDH1A1 | |
| SCHEMBL31176940 | 0.79 | MAPT (0.49) | VCAM1TDP1TSHRMAPTLMNA | |
| SCHEMBL20982744 | 0.79 | MAPT (0.49) | VCAM1TDP1TSHRMAPTLMNA | |
| SCHEMBL18789074 | 0.79 | TDP1 (0.59) | TDP1TSHRMAPTRECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651801-A | Fluorescent probe for selectively identifying fluorine ions and preparation method thereof | 长春工业大学 | 2021-11-16 | — | — | CN | claimed |
| CN-116120190-B | Method for preparing o-nitroaniline compound and application of o-nitroaniline compound | 邵阳学院 | 2024-08-23 | — | — | CN | disclosed |
| US-20240059703-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | AMGEN INC. | 2024-02-22 | — | — | US | disclosed |
| EP-4232444-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | Amgen Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| CN-116120190-A | Method for preparing o-nitroaniline compound and application of o-nitroaniline compound | 邵阳学院 | 2023-05-16 | — | — | CN | disclosed |
| CN-113651801-B | Fluorescent probe for selectively identifying fluorine ions and preparation method thereof | 长春工业大学 | 2022-10-28 | — | — | CN | disclosed |
| CN-114524770-B | Bis-benzimidazole fluorescent dye, preparation method and application thereof | 天津全和诚科技有限责任公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-114524770-A | Bis-benzimidazole fluorescent dye, preparation method and application thereof | 天津全和诚科技有限责任公司 | 2022-05-24 | — | — | CN | disclosed |
| WO-2022083569-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | AMGEN INC. (US) | 2022-04-28 | — | — | WO | disclosed |
| CN-113651801-A | Fluorescent probe for selectively identifying fluorine ions and preparation method thereof | 长春工业大学 | 2021-11-16 | — | — | CN | disclosed |
| WO-2005030705-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2005-04-07 | — | — | WO | disclosed |
| US-20040254159-A1 | Heterocyclic kinase inhibitors | ABBOTT LABORATORIES | 2004-12-16 | — | — | US | disclosed |
| WO-2004085046-A2 | METHOD FOR SELECTIVELY BINDING A SUBSTRATE TO SORBENTS BY WAY OF AT LEAST BIVALENT BONDS | INSTRACTION GMBH (DE) | 2004-10-07 | — | — | WO | disclosed |
| WO-2004076424-A1 | HETEROCYCLIC KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2004-09-10 | — | — | WO | disclosed |
| US-6221914-B1 | ANTIINFLAMMATORY AGENTS | ARRAY BIOPHARMA INC. | 2001-04-24 | — | — | US | disclosed |
| WO-1999024395-A1 | COMPOUNDS WHICH INHIBIT TRYPTASE ACTIVITY | ARRAY BIOPHARMA, INC. (US) | 1999-05-20 | — | — | WO | disclosed |
| EP-0209707-A2 | 2-Aryl imidazoles, pharmaceutical compositions containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1987-01-28 | — | — | EP | disclosed |
| EP-0071035-B1 | REACTIVE MONO-FUNCTIONAL BISAZO BLUE-BLACK DYE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-11-07 | — | — | EP | disclosed |
| US-4464297-A | Fiber reactive bisazo dye having both a vinylsulfone type reactive group and an ortho-nitrophenyl group | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-08-07 | — | — | US | disclosed |
| EP-0071035-A1 | Reactive mono-functional bisazo blue-black dye | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-02-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040254159-A1 | Heterocyclic kinase inhibitors | MAP3K20, MAP3K19, MAP3K1 | VCAM1 3236/4885TDP1 1112/4885TSHR 4139/4885 |
| US-20240059703-A1 | HETEROCYCLIC SPIRO COMPOUNDS AND METHODS OF USE | KRAS, HRAS, APC | VCAM1 4453/4885TDP1 4325/4885TSHR 4163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.