Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.61 |
| ▸ | BACE1 | P56817 | 1/20 | 0.61 |
| ▸ | XDH | P47989 | 1/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CNR2 | P34972 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | PPARD | Q03181 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857942 | 0.98 | NUDT1 (0.59) | NUDT1BACE1XDHGABRA1GABRB2 | |
| SCHEMBL11815056 | 0.82 | NUDT1 (0.43) | NUDT1BACE1XDHGABRA1GABRB2 | |
| SCHEMBL7182409 | 0.82 | NUDT1 (0.71) | NUDT1BACE1MEN1KMT2AMAPT | |
| SCHEMBL10597858 | 0.82 | BACE1 (0.81) | NUDT1BACE1ALDH1A1MAPTGAA | |
| SCHEMBL10917666 | 0.81 | MEN1 (0.43) | NUDT1BACE1XDHGABRA1GABRB2 | |
| SCHEMBL27749308 | 0.80 | NUDT1 (0.69) | NUDT1BACE1MEN1KMT2AMAPT | |
| SCHEMBL28427162 | 0.79 | MAPT (0.42) | NUDT1BACE1XDHGABRA1GABRB2 | |
| SCHEMBL10595253 | 0.79 | NUDT1 (0.77) | NUDT1BACE1HSP90AA1THRBTHRA | |
| SCHEMBL10596917 | 0.79 | NUDT1 (0.77) | NUDT1BACE1HSP90AA1THRBTHRA | |
| SCHEMBL13586652 | 0.79 | NUDT1 (0.67) | NUDT1BACE1CNR2CNR1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174277-B1 | ANTI-OXIDANT COMPOSITONS FOR ORGANIC MATERIAL | CIBA-GEIGY AG (CH) | 1988-04-06 | — | — | EP | disclosed |
| US-4691044-A | REACTING SULFUR WITH PHENOL DERIVATIVE | CIBA-GEIGY CORPORATION (US) | 1987-09-01 | — | — | US | disclosed |
| EP-0174277-A1 | Anti-oxidant compositons for organic material | CIBA-GEIGY AG (CH) | 1986-03-12 | — | — | EP | disclosed |