Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.66 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.64 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.64 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | DRD3 | P35462 | 3/20 | 0.60 |
| ▸ | DRD2 | P14416 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.59 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.59 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036874 | 0.99 | LTA4H (0.67) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL10685703 | 0.88 | LTA4H (0.70) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL5725767 | 0.88 | LTA4H (0.67) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL10676277 | 0.86 | LTA4H (0.71) | LTA4HPSMB1PSMB5PSMB2HTT | |
| SCHEMBL7205222 | 0.84 | LTA4H (0.62) | LTA4HPSMB1PSMB5PSMB2ALDH1A1 | |
| SCHEMBL15257179 | 0.83 | LTA4H (0.82) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL14970684 | 0.83 | LTA4H (0.82) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL12315758 | 0.82 | KDM4E (0.63) | LTA4HPSMB1PSMB5PSMB2HRH3 | |
| SCHEMBL14287617 | 0.82 | SMN1; SMN2 (0.76) | PSMB1PSMB5PSMB2HRH3ALDH1A1 | |
| SCHEMBL4092312 | 0.82 | PSMB1 (0.66) | LTA4HPSMB1PSMB5PSMB2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4764533-A | ANTITUMOR | KLINGE PHARMA GMBH (DE) | 1988-08-16 | — | — | US | disclosed |