Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | NEK2 | P51955 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10681618 | 0.87 | KDM4E (0.46) | KDM4EHSD17B10POLBCYP3A4CYP2C9 | |
| SCHEMBL10687459 | 0.84 | KDM4E (0.49) | KDM4EHSD17B10POLBCYP3A4CYP2C9 | |
| SCHEMBL10690052 | 0.80 | CHEK1 (0.48) | KDM4EPOLBCHEK1NEK2LIMK1 | |
| SCHEMBL10688298 | 0.75 | PDE4A (0.51) | KDM4EPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL10685619 | 0.74 | CTSS (0.43) | KDM4EHSD17B10POLBCYP3A4CYP2C9 | |
| SCHEMBL10691334 | 0.74 | TSHR (0.47) | KDM4EHSD17B10POLBCYP3A4CYP2C9 | |
| SCHEMBL10685963 | 0.72 | SMN1; SMN2 (0.51) | HSD17B10METMEN1KMT2AUSP2 | |
| SCHEMBL10685758 | 0.72 | CTSS (0.48) | KDM4EHSD17B10POLBCYP3A4PDE4D | |
| SCHEMBL10683598 | 0.70 | PARP1 (0.43) | KDM4EHSD17B10POLBCYP3A4CYP2C9 | |
| SCHEMBL11373461 | 0.68 | MAPT (0.39) | KDM4EPOLBCHEK1NEK2LIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738961-A | FUNGICIDES | SANKYO COMPANY, LIMITED (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0072238-B1 | PYRIDAZINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN AGRICULTURAL COMPOSITIONS AND THE TREATMENT OF SEED AND PLANTS | SANKYO COMPANY LIMITED (JP) | 1985-11-06 | — | — | EP | disclosed |
| EP-0072238-A1 | Pyridazinone derivatives, their preparation and their use in agricultural compositions and the treatment of seed and plants | SANKYO COMPANY LIMITED (JP) | 1983-02-16 | — | — | EP | disclosed |