Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MET | P08581 | 6/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685952 | 0.91 | MEN1 (0.51) | TSHRMEN1KMT2AMETHTT | |
| SCHEMBL10690994 | 0.89 | MEN1 (0.49) | MEN1KMT2AMETPOLBHTT | |
| SCHEMBL10685139 | 0.88 | MEN1 (0.48) | MEN1KMT2AMETPOLBHTT | |
| SCHEMBL10687459 | 0.80 | KDM4E (0.49) | TSHRMEN1KMT2AMETPOLB | |
| SCHEMBL10681289 | 0.77 | MEN1 (0.54) | TSHRMEN1KMT2AMETHTT | |
| SCHEMBL10687571 | 0.77 | MEN1 (0.54) | TSHRMEN1KMT2AMETPOLB | |
| SCHEMBL10681618 | 0.76 | KDM4E (0.46) | TSHRMEN1KMT2AMETPOLB | |
| SCHEMBL10688671 | 0.74 | KDM4E (0.43) | TSHRMEN1KMT2AMETPOLB | |
| SCHEMBL10689612 | 0.74 | MEN1 (0.54) | MEN1KMT2AMETHTTLMNA | |
| SCHEMBL10688478 | 0.71 | PDE4D (0.49) | MEN1KMT2APRKDCPOLBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738961-A | FUNGICIDES | SANKYO COMPANY, LIMITED (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0072238-B1 | PYRIDAZINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN AGRICULTURAL COMPOSITIONS AND THE TREATMENT OF SEED AND PLANTS | SANKYO COMPANY LIMITED (JP) | 1985-11-06 | — | — | EP | disclosed |
| EP-0072238-A1 | Pyridazinone derivatives, their preparation and their use in agricultural compositions and the treatment of seed and plants | SANKYO COMPANY LIMITED (JP) | 1983-02-16 | — | — | EP | disclosed |