Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.46 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.43 |
| ▸ | NQO2 | P16083 | 3/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10689067 | 1.00 | MTNR1A (0.46) | MTNR1AGRM7MTNR1BNQO2HCRTR1 | |
| SCHEMBL24614089 | 0.89 | MTNR1A (0.46) | MTNR1AGRM7MTNR1BHCRTR1HCRTR2 | |
| SCHEMBL10692134 | 0.81 | HTR1A (0.43) | MTNR1AGRM7HCRTR1HCRTR2TP53 | |
| SCHEMBL10692133 | 0.81 | HTR1A (0.43) | MTNR1AGRM7HCRTR1HCRTR2TP53 | |
| Hydrochloric Acid SCHEMBL10691710 | 0.81 | HTR1A (0.42) | MTNR1AGRM7HCRTR1HCRTR2TP53 | |
| Hydrochloric Acid SCHEMBL10691714 | 0.81 | HTR1A (0.42) | MTNR1AGRM7HCRTR1HCRTR2TP53 | |
| SCHEMBL10611473 | 0.79 | HTR1A (0.44) | MTNR1AMTNR1BNQO2HCRTR1HCRTR2 | |
| SCHEMBL10611460 | 0.79 | HTR1A (0.44) | MTNR1AMTNR1BNQO2HCRTR1HCRTR2 | |
| SCHEMBL10611463 | 0.79 | HTR1A (0.44) | MTNR1AMTNR1BNQO2HCRTR1HCRTR2 | |
| SCHEMBL7272279 | 0.78 | MTNR1A (0.60) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792548-A | Trans-benzopyran-(4,3-b)-1,4-oxazine derivatives, intermediates and pharmaceutical use | WARNER-LAMBERT COMPANY (US) | 1988-12-20 | — | — | US | disclosed |