Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10684229 | 0.90 | PPARG (0.46) | ALDH1A1NPSR1PPARGHPGDKMT2A | |
| SCHEMBL10687839 | 0.86 | ALDH1A1 (0.52) | ALDH1A1NPSR1PPARGHPGDKMT2A | |
| SCHEMBL10684367 | 0.83 | PPARG (0.43) | ALDH1A1NPSR1PPARGHPGDKMT2A | |
| SCHEMBL10690377 | 0.82 | PPARG (0.50) | ALDH1A1NPSR1PPARGKMT2AMAPT | |
| SCHEMBL10686496 | 0.82 | FFAR1 (0.55) | ALDH1A1PPARGHPGDKMT2AMEN1 | |
| SCHEMBL10687947 | 0.81 | ALDH1A1 (0.54) | ALDH1A1NPSR1PPARGHPGDKMT2A | |
| SCHEMBL10687997 | 0.79 | PPARG (0.48) | ALDH1A1NPSR1PPARGMAPTFFAR1 | |
| SCHEMBL10688715 | 0.79 | ALDH1A1 (0.46) | ALDH1A1HPGDKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL13598453 | 0.77 | FFAR1 (0.48) | ALDH1A1NPSR1PPARGPOLBMAPT | |
| SCHEMBL31476393 | 0.76 | ADRB3 (0.52) | ALDH1A1KMT2AMEN1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738972-A | Hypoglycemic thiazolidinediones | PFIZER INC. (US) | 1988-04-19 | — | — | US | disclosed |