Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10683484 | 0.90 | PPARG (0.49) | PPARGFFAR1ALDH1A1NPSR1MAPT | |
| SCHEMBL10685775 | 0.87 | PPARG (0.49) | PPARGFFAR1ALDH1A1NPSR1MAPT | |
| SCHEMBL10691350 | 0.81 | MTNR1A (0.54) | PPARGMTNR1AMTNR1B | |
| SCHEMBL10688765 | 0.81 | MTNR1A (0.41) | PPARGFFAR1MAPTMTNR1AMTNR1B | |
| SCHEMBL10689541 | 0.79 | ALDH1A1 (0.49) | PPARGFFAR1ALDH1A1NPSR1MAPT | |
| SCHEMBL10689825 | 0.78 | MTNR1A (0.46) | MTNR1AMTNR1B | |
| SCHEMBL10690377 | 0.77 | PPARG (0.50) | PPARGFFAR1ALDH1A1NPSR1MAPT | |
| SCHEMBL10691392 | 0.77 | CYP26A1 (0.56) | PPARGFFAR1ALDH1A1NPSR1MAPT | |
| SCHEMBL10690190 | 0.77 | PPARG (0.52) | PPARGFFAR1ALDH1A1NPSR1MAPT | |
| SCHEMBL10686431 | 0.77 | PPARG (0.52) | PPARGFFAR1ALDH1A1NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738972-A | Hypoglycemic thiazolidinediones | PFIZER INC. (US) | 1988-04-19 | — | — | US | disclosed |