Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.30 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10377999 | 0.82 | SRD5A1 (0.40) | CYP1A2CYP11B1CYP11B2TYMSSRD5A1 | |
| SCHEMBL10379371 | 0.82 | SRD5A1 (0.37) | CYP1A2CYP11B1CYP11B2TYMSDAO | |
| SCHEMBL10685831 | 0.77 | CYP19A1 (0.35) | CYP11B1CYP11B2TYMSDDB1CRBN | |
| SCHEMBL10686542 | 0.77 | SRD5A1 (0.37) | TYMSDAOSRD5A1DDB1CRBN | |
| SCHEMBL7594487 | 0.75 | CYP11B1 (0.42) | CYP1A2CYP11B1CYP11B2DDB1CRBN | |
| SCHEMBL10688754 | 0.74 | KDM4E (0.37) | — | |
| SCHEMBL10689321 | 0.73 | ABL1 (0.39) | CYP1A2CYP11B1CYP11B2TYMS | |
| SCHEMBL16823586 | 0.66 | AHR (0.43) | CYP1A2CYP11B1CYP11B2SRD5A1DDB1 | |
| SCHEMBL25212070 | 0.64 | CYP1A2 (0.33) | CYP1A2CYP11B1CYP11B2TYMSDDB1 | |
| SCHEMBL29362083 | 0.64 | CYP1A2 (0.33) | CYP1A2CYP11B1CYP11B2TYMSDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4742061-A | Benzoc[c]-1,5-naphthyridines and related compounds as memory enhancing agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-05-03 | — | — | US | claimed |
| US-4742061-A | Benzoc[c]-1,5-naphthyridines and related compounds as memory enhancing agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-05-03 | — | — | US | disclosed |