Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 3/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10379371 | 0.83 | SRD5A1 (0.37) | SRD5A1TYMSALDH1A1LMNAGABRA1 | |
| SCHEMBL10688708 | 0.83 | LMNA (0.36) | IDO1TYMSCHEK1ALDH1A1LMNA | |
| SCHEMBL7594487 | 0.79 | CYP11B1 (0.42) | ALDH1A1LMNAPARP1DDB1CRBN | |
| SCHEMBL10689555 | 0.77 | CYP1A2 (0.36) | SRD5A1TYMSDAODDB1CRBN | |
| SCHEMBL10379456 | 0.75 | KMT2A (0.38) | ALDH1A1GABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL10377999 | 0.74 | SRD5A1 (0.40) | SRD5A1TYMSCHEK1GABRA1GABRG2 | |
| SCHEMBL10685831 | 0.74 | CYP19A1 (0.35) | TYMSCHEK1MAPTCASP3DDB1 | |
| SCHEMBL3515984 | 0.67 | NPC1 (0.35) | SRD5A1LMNAMAPTCRBN | |
| SCHEMBL30147487 | 0.64 | TAAR1 (0.31) | TAAR1CASP3SENP8SENP7SENP6 | |
| SCHEMBL24861377 | 0.63 | CRBN (0.56) | IDO1ALDH1A1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4742061-A | Benzoc[c]-1,5-naphthyridines and related compounds as memory enhancing agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-05-03 | — | — | US | claimed |
| US-4742061-A | Benzoc[c]-1,5-naphthyridines and related compounds as memory enhancing agents | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-05-03 | — | — | US | disclosed |