SCHEMBL10689705

SCHEMBL10689705

CCN1CCCc2cc(C=O)ccc21

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 13/20 0.66
MEN1 O00255 7/20 0.66
KMT2A Q03164 7/20 0.66
MAPT P10636 6/20 0.66
HPGD P15428 5/20 0.66
GAA P10253 4/20 0.66
HRH3 Q9Y5N1 2/20 0.48
ALDH1A3 P47895 5/20 0.45
KDM4E B2RXH2 4/20 0.43
LMNA P02545 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
HTT P42858 2/20 0.43
TP53 P04637 1/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
SMAD3 P84022 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CHRM2 P08172 1/20 0.42
CHRM4 P08173 1/20 0.42
CHRM1 P11229 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL574432 0.91 ALDH1A1 (0.56) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL11452892 0.88 HRH3 (0.50) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL11452893 0.88 HRH3 (0.50) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL7487255 0.86 MAPT (0.63) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL26941412 0.85 HRH3 (0.48) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL7035556 0.84 MEN1 (0.60) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL2203358 0.84 MEN1 (0.60) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL11576297 0.84 HRH3 (0.50) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL29100113 0.82 ALDH1A1 (0.62) ALDH1A1MEN1KMT2AMAPTHPGD
SCHEMBL11117991 0.82 ALDH1A1 (0.58) ALDH1A1MEN1KMT2AMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4738972-A Hypoglycemic thiazolidinediones PFIZER INC. (US) 1988-04-19 US disclosed
EP-0039025-B1 DERIVATIVES OF ARYL KETONES AS SENSITIZERS OF PHOTOPOLYMERIZABLE COMPOUNDS FOR THE VISIBLE SPECTRAL RANGE, AND PHOTOPOLYMERIZABLE COMPOSITIONS COMPRISING THE SAID SENSITIZERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-03-14 EP disclosed
US-4351893-A TRIARYLIMIDAZOLE DIMER INITIATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-09-28 US disclosed
EP-0039025-A1 Derivatives of aryl ketones as sensitizers of photopolymerizable compounds for the visible spectral range, and photopolymerizable compositions comprising the said sensitizers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-11-04 EP disclosed
US-4268667-A Derivatives of aryl ketones based on 9,10-dihydro-9,10-ethanoanthracene and p-dialkyl-aminoaryl aldehydes as visible sensitizers for photopolymerizable compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 1981-05-19 US disclosed
US-RE30235-E FOR ELECTROPHORETIC MIGRATION IMAGING PROCESSES EASTMAN KODAK COMPANY (US) 1980-03-18 US disclosed
US-4012376-A Photosensitive colorant materials EASTMAN KODAK COMPANY (US) 1977-03-15 US disclosed