Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19873004 | 0.86 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL21248477 | 0.85 | MEN1 (0.58) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL7487255 | 0.83 | MAPT (0.63) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL18902663 | 0.83 | MEN1 (0.51) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL10689705 | 0.82 | ALDH1A1 (0.66) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL2118792 | 0.81 | MEN1 (0.49) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL7035556 | 0.81 | MEN1 (0.60) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL2203358 | 0.81 | MEN1 (0.60) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL10691421 | 0.81 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL1105690 | 0.81 | MEN1 (0.53) | ALDH1A1MEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116969981-A | Dihydroquinoline compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2023-10-31 | — | — | CN | disclosed |