Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.60 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10992160 | 0.91 | ABCG2 (0.58) | PLK1L3MBTL1ABCG2MEN1KMT2A | |
| SCHEMBL28402209 | 0.88 | TP53 (0.69) | ABCG2TP53TSHRPLA2G4BGAA | |
| SCHEMBL28980597 | 0.88 | TP53 (0.69) | ABCG2TP53TSHRPLA2G4BGAA | |
| SCHEMBL10990486 | 0.88 | TP53 (0.69) | ABCG2TP53TSHRPLA2G4BGAA | |
| Water SCHEMBL7212248 | 0.87 | TP53 (0.67) | ABCG2TP53TSHRPLA2G4BGAA | |
| Water SCHEMBL7207837 | 0.87 | TP53 (0.67) | ABCG2TP53TSHRPLA2G4BGAA | |
| SCHEMBL3039297 | 0.85 | PLK1 (0.62) | PLK1ABCG2KMT2AMAPTPLA2G4B | |
| SCHEMBL9786100 | 0.84 | GAA (0.59) | PLK1L3MBTL1ABCG2MAPTMAPK1 | |
| SCHEMBL5108830 | 0.82 | L3MBTL1 (0.46) | PLK1L3MBTL1ABCG2MAPTMAPK1 | |
| SCHEMBL6341040 | 0.81 | L3MBTL1 (0.68) | PLK1L3MBTL1KMT2ATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252406-A2 | Process for the manufacture of polycyclic compounds | BAYER AG (DE) | 1988-01-13 | — | — | EP | disclosed |