Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | PLA2G4B | P0C869 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28980597 | 0.93 | TP53 (0.69) | ABCG2TP53TSHRPLA2G4BRARB | |
| SCHEMBL28402209 | 0.93 | TP53 (0.69) | ABCG2TP53TSHRPLA2G4BRARB | |
| SCHEMBL10990486 | 0.93 | TP53 (0.69) | ABCG2TP53TSHRPLA2G4BRARB | |
| Water SCHEMBL7207837 | 0.92 | TP53 (0.67) | ABCG2TP53TSHRPLA2G4BRARB | |
| Water SCHEMBL7212248 | 0.92 | TP53 (0.67) | ABCG2TP53TSHRPLA2G4BRARB | |
| SCHEMBL10689975 | 0.91 | PLK1 (0.65) | ABCG2TP53TSHRPLA2G4BL3MBTL1 | |
| SCHEMBL3039297 | 0.84 | PLK1 (0.62) | ABCG2PLA2G4BPLK1KMT2A | |
| SCHEMBL27424165 | 0.83 | THRB (0.63) | ABCG2TP53TSHRPLA2G4BL3MBTL1 | |
| SCHEMBL9786100 | 0.82 | GAA (0.59) | ABCG2L3MBTL1PLK1ALDH1A1GAA | |
| SCHEMBL5108830 | 0.81 | L3MBTL1 (0.46) | ABCG2L3MBTL1PLK1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4536517-A | ANTIDIABETIC, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1985-08-20 | — | — | US | disclosed |