SCHEMBL10690024

SCHEMBL10690024

CCOCCOCCOc1ccc(-c2ccc(O)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 0.53
NR5A1 Q13285 1/20 0.53
APP P05067 2/20 0.53
RARB P10826 2/20 0.53
ESR2 Q92731 2/20 0.47
THRA P10827 1/20 0.47
RARA P10276 1/20 0.46
KDM4E B2RXH2 1/20 0.45
RECQL P46063 1/20 0.45
ADRB2 P07550 1/20 0.44
ADRB1 P08588 1/20 0.44
ADRB3 P13945 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP19A1 P11511 2/20 0.43
ESR1 P03372 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10694518 0.94 LTA4H (0.58) LTA4HNR5A1APPRARBESR2
SCHEMBL321723 0.93 LTA4H (0.60) LTA4HNR5A1APPESR2THRA
SCHEMBL4354892 0.91 APP (0.61) LTA4HNR5A1APPRARBESR2
SCHEMBL4059613 0.89 RARB (0.53) RARBTHRARARAKDM4ERECQL
SCHEMBL6937465 0.88 RARB (0.68) LTA4HNR5A1APPRARBRARA
SCHEMBL16305604 0.86 APP (0.53) LTA4HNR5A1APPRARBESR2
SCHEMBL9150174 0.84 KDM4E (0.56) APPRARBTHRAKDM4ERECQL
SCHEMBL6860317 0.84 APP (0.67) LTA4HNR5A1APPESR2KDM4E
SCHEMBL2471330 0.84 APP (0.67) LTA4HNR5A1APPESR2KDM4E
SCHEMBL19284359 0.84 APP (0.67) LTA4HNR5A1APPESR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0256303-A2 Liquid crystal compounds having fluorine-containing core POLAROID CORPORATION (US) 1988-02-24 EP disclosed