Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.60 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 2/20 | 0.54 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | NCF1 | P14598 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694518 | 0.98 | LTA4H (0.58) | LTA4HNR5A1APPTHRAADRB2 | |
| SCHEMBL10690024 | 0.93 | LTA4H (0.53) | LTA4HNR5A1APPTHRAADRB2 | |
| SCHEMBL4061378 | 0.89 | NQO1 (0.57) | LTA4HTHRANCF1CYP1A2CYP3A4 | |
| SCHEMBL16561442 | 0.88 | THRA (0.57) | LTA4HNR5A1APPTHRAADRB2 | |
| SCHEMBL16561490 | 0.88 | THRA (0.57) | LTA4HNR5A1THRAADRB2ADRB1 | |
| SCHEMBL10704555 | 0.87 | LTA4H (0.76) | LTA4HNR5A1APPESR1CYP19A1 | |
| SCHEMBL9150174 | 0.87 | KDM4E (0.56) | APPTHRANCF1CYP1A2CYP3A4 | |
| SCHEMBL2471330 | 0.87 | APP (0.67) | LTA4HNR5A1APPESR1ESR2 | |
| SCHEMBL19284359 | 0.87 | APP (0.67) | LTA4HNR5A1APPESR1ESR2 | |
| SCHEMBL6860317 | 0.87 | APP (0.67) | LTA4HNR5A1APPESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748307-A1 | SKIN LIGHTENING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-12-18 | — | — | EP | claimed |
| WO-1995023780-A2 | SKIN LIGHTENING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1995-09-08 | — | — | WO | claimed |
| CN-110387035-B | Demulsifier, preparation method thereof and application thereof in demulsification of thick oil containing asphaltene | 中国石油化工股份有限公司 | 2022-01-04 | — | — | CN | disclosed |
| CN-110387035-A | Demulsifier and preparation method thereof and the application in asphaltenes thick oil emulsion breaking | 中国石油化工股份有限公司 | 2019-10-29 | — | — | CN | disclosed |
| EP-1856198-B1 | WATER ACTIVATED OXYGEN SCAVENGING COMPOSITION | MULTISORB TECH INC (US) | 2014-11-19 | — | — | EP | disclosed |
| US-20130261178-A1 | PHENOXYPROPANOL DERIVATIVES AND THEIR USE IN TREATING CARDIAC AND CARDIOVASCULAR DISEASES | MISTRY SHAILESH (GB) | 2013-10-03 | — | — | US | disclosed |
| EP-2590937-A1 | PHENOXYPROPANOL DERIVATIVES AND THEIR USE IN TREATING CARDIAC AND CARDIOVASCULAR DISEASES | The University Of Nottingham (GB) | 2013-05-15 | — | — | EP | disclosed |
| US-8277892-B2 | Process for creating an oxygen scavenging particle | MULTISORB TECHNOLOGIES, INC. (US) | 2012-10-02 | — | — | US | disclosed |
| WO-2012004549-A1 | PHENOXYPROPANOL DERIVATIVES AND THEIR USE IN TREATING CARDIAC AND CARDIOVASCULAR DISEASES | THE UNIVERSITY OF NOTTINGHAM (GB) | 2012-01-12 | — | — | WO | disclosed |
| EP-1797213-B8 | METHOD OF MAKING VAPOUR DEPOSITED OXYGEN-SCAVENGING PARTICLES | MULTISORB TECH INC (US) | 2011-10-12 | — | — | EP | disclosed |
| EP-1797213-B1 | METHOD OF MAKING VAPOUR DEPOSITED OXYGEN-SCAVENGING PARTICLES | M & G POLIMERI ITALIA SPA (IT) | 2011-07-27 | — | — | EP | disclosed |
| US-20030100616-A1 | 3-AMINO-PROPOXYPHENYL DERIVATIVES (I) | LOUIS, WILLIAM JOHN, AUSTIN AND REPATRIATION MEDICAL CENTRE (AU) | 2003-05-29 | — | — | US | disclosed |
| EP-0937030-A4 | 3-AMINO-PROPOXYPHENYL DERIVATIVES (I) | UNIV MELBOURNE (AU) | 2000-06-07 | — | — | EP | disclosed |
| EP-0937030-A1 | 3-AMINO-PROPOXYPHENYL DERIVATIVES (I) | THE UNIVERSITY OF MELBOURNE (AU) | 1999-08-25 | — | — | EP | disclosed |
| WO-1997013744-A1 | 3-AMINO-PROPOXYPHENYL DERIVATIVES (I) | THE UNIVERSITY OF MELBOURNE (AU) | 1997-04-17 | — | — | WO | disclosed |
| EP-0748307-A1 | SKIN LIGHTENING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1996-12-18 | — | — | EP | disclosed |
| WO-1995023780-A2 | SKIN LIGHTENING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1995-09-08 | — | — | WO | disclosed |
| US-4734471-A | Method of curing polyfluoroalkoxyphosphazene | ETHYL CORPORATION (US) | 1988-03-29 | — | — | US | disclosed |
| US-4088764-A | CARDIOVASCULAR DISORDERS, BETA-ADRENERGIC BLOCKING AGENTS, ANTIARRHYTHMIC AGENTS | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4066768-A | ADRENERGIC BLOCKING AGENTS, ANTIARRHYTHMIC | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1978-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130261178-A1 | PHENOXYPROPANOL DERIVATIVES AND THEIR USE IN TREATING CARDIAC AND CARDIOVASCULAR DISEASES | NR3C2, NPR3, ADRB3 | LTA4H 2032/4885NR5A1 98/4885APP 1892/4885 |
| US-20030100616-A1 | 3-AMINO-PROPOXYPHENYL DERIVATIVES (I) | ADRB1, ADRB3, ADRB2 | LTA4H 2013/4885NR5A1 632/4885APP 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.