Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23620796 | 0.83 | APP (0.48) | OPRD1PTGS2APPABL1ABCB1 | |
| SCHEMBL11520829 | 0.81 | ESR1 (0.59) | OPRD1PTGS2APPABL1ABCB1 | |
| SCHEMBL10844385 | 0.80 | OPRD1 (0.56) | OPRD1PTGS2APPABL1ABCB1 | |
| SCHEMBL10844270 | 0.80 | OPRD1 (0.56) | OPRD1PTGS2APPABL1ABCB1 | |
| SCHEMBL8985277 | 0.80 | OPRD1 (0.56) | OPRD1PTGS2APPABL1ABCB1 | |
| SCHEMBL11521840 | 0.80 | ESR1 (0.53) | OPRD1PTGS2APPALOX5KDM4E | |
| SCHEMBL10953432 | 0.77 | OPRD1 (0.54) | OPRD1PTGS2APPABL1ABCB1 | |
| SCHEMBL11043188 | 0.77 | OPRD1 (0.54) | OPRD1PTGS2APPABL1ABCB1 | |
| SCHEMBL10683946 | 0.77 | OPRD1 (0.57) | OPRD1PTGS2APPABL1ABCB1 | |
| SCHEMBL10912450 | 0.77 | OPRD1 (0.54) | OPRD1PTGS2APPABL1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4749712-A | Antiinflammatory and/or analgesic 5-alkylthiophenes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-06-07 | — | — | US | disclosed |