Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690054 | 0.80 | OPRD1 (0.58) | OPRD1PTGS2APPMAPTKDM4E | |
| SCHEMBL11520829 | 0.80 | ESR1 (0.59) | OPRD1PTGS2APPMAPTALDH1A1 | |
| SCHEMBL10844385 | 0.79 | OPRD1 (0.56) | OPRD1PTGS2APPMAPTKDM4E | |
| SCHEMBL10844270 | 0.79 | OPRD1 (0.56) | OPRD1PTGS2APPMAPTKDM4E | |
| SCHEMBL10683946 | 0.76 | OPRD1 (0.57) | OPRD1PTGS2APPMAPTKDM4E | |
| SCHEMBL11043188 | 0.76 | OPRD1 (0.54) | OPRD1PTGS2APPMAPTKDM4E | |
| SCHEMBL10912450 | 0.76 | OPRD1 (0.54) | OPRD1PTGS2APPMAPTKDM4E | |
| SCHEMBL10953432 | 0.76 | OPRD1 (0.54) | OPRD1PTGS2APPMAPTKDM4E | |
| SCHEMBL8689168 | 0.76 | OPRD1 (0.54) | OPRD1PTGS2APPBACE1ABL1 | |
| SCHEMBL28707645 | 0.75 | PTGS2 (0.49) | PTGS2BACE1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| EP-0593761-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-27 | — | — | EP | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |