Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 8/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10991686 | 0.88 | POLB (0.60) | KLK7POLBCNR1KMT2AMAPT | |
| SCHEMBL10692448 | 0.84 | POLB (0.59) | POLBCNR1TSHRKMT2A | |
| SCHEMBL10694396 | 0.84 | KLK7 (0.60) | KLK7TSHRMEN1KMT2ACRHBP | |
| SCHEMBL10695946 | 0.80 | POLB (0.57) | POLBCNR1MEN1KMT2AMAPT | |
| SCHEMBL10695951 | 0.80 | POLB (0.57) | POLBCNR1KMT2A | |
| SCHEMBL8460316 | 0.79 | TSHR (0.61) | KLK7TSHRMEN1KMT2ACRHBP | |
| SCHEMBL10689564 | 0.77 | CNR1 (0.63) | CNR1KMT2A | |
| SCHEMBL10693205 | 0.76 | KLK7 (0.53) | KLK7POLBCNR1KMT2AMAPT | |
| SCHEMBL10694651 | 0.76 | POLB (0.47) | KLK7POLBCNR1MAPT | |
| SCHEMBL10694408 | 0.76 | TSHR (0.57) | KLK7TSHRMEN1KMT2ACRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |