Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695946 | 0.82 | POLB (0.57) | POLBCNR1KDM4ACA12CA2 | |
| SCHEMBL10692448 | 0.81 | POLB (0.59) | POLBCNR1SMN1; SMN2RECQLKDM4A | |
| SCHEMBL29291234 | 0.80 | CTSD (0.51) | HTTSMN1; SMN2RECQLCYP2D6CYP2C9 | |
| SCHEMBL10690093 | 0.80 | KLK7 (0.57) | POLBCNR1KMT2A | |
| SCHEMBL10991686 | 0.79 | POLB (0.60) | POLBCNR1SMN1; SMN2RECQLKDM4A | |
| SCHEMBL13569363 | 0.78 | CNR1 (0.81) | POLBCNR1HTTSMN1; SMN2CNR2 | |
| SCHEMBL8870449 | 0.78 | ALDH1A1 (0.52) | HTTSMN1; SMN2RECQLCYP2D6CYP2C9 | |
| SCHEMBL5222146 | 0.78 | POLB (0.46) | POLBCNR1HTTSMN1; SMN2KDM4A | |
| SCHEMBL1586340 | 0.77 | SLC1A3 (0.54) | HTTSMN1; SMN2RECQLCYP2D6CYP2C9 | |
| SCHEMBL8974580 | 0.76 | POLB (0.65) | POLBCNR1KDM4ACA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |