Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KLK7 | P49862 | 7/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | PAM | P19021 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8460316 | 0.86 | TSHR (0.61) | TSHRKLK7ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL10983198 | 0.81 | CYP3A4 (0.44) | TSHRKLK7EPHX1ALDH1A1KMT2A | |
| SCHEMBL28555706 | 0.80 | TSHR (0.57) | TSHRKLK7ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL4911331 | 0.79 | CRHBP (0.69) | TSHRKLK7ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8054787 | 0.79 | TSHR (0.65) | TSHRKLK7ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL24998379 | 0.79 | L3MBTL1 (0.49) | KLK7EPHX1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL30183305 | 0.79 | L3MBTL1 (0.49) | KLK7EPHX1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL27336664 | 0.78 | ALDH1A1 (0.46) | EPHX1ALDH1A1MAPK1KMT2A | |
| SCHEMBL17491377 | 0.78 | SMN1; SMN2 (0.48) | EPHX1ALDH1A1MAPK1KMT2A | |
| SCHEMBL28544611 | 0.77 | TSHR (0.54) | TSHRKLK7ALDH1A1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |