Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.62 |
| ▸ | NOTUM | Q6P988 | 11/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4805950 | 0.78 | EGLN2 (1.00) | EGLN2NOTUMADRB1NPSR1 | |
| Hydrochloric Acid SCHEMBL2570457 | 0.77 | EGLN2 (0.98) | EGLN2NOTUMADRB1NPSR1 | |
| SCHEMBL10688400 | 0.77 | NOTUM (0.50) | EGLN2NOTUMCYP1A2CYP2C9CHRNB2 | |
| SCHEMBL27150414 | 0.77 | ADRB1 (0.49) | EGLN2NOTUMADRB1NOS3NOS2 | |
| Hydrochloric Acid SCHEMBL27768988 | 0.76 | EGLN2 (0.52) | EGLN2NOTUMADRB1NOS3NOS2 | |
| SCHEMBL10691838 | 0.75 | NOTUM (0.49) | EGLN2NOTUMCYP1A2CYP2C9CHRNB2 | |
| SCHEMBL1164215 | 0.75 | NOTUM (0.53) | EGLN2NOTUMKEAP1 | |
| SCHEMBL14909193 | 0.74 | EGLN2 (0.40) | EGLN2NOTUMKEAP1 | |
| SCHEMBL29850186 | 0.74 | EGLN2 (0.40) | EGLN2NOTUMKEAP1KDM4EALDH1A1 | |
| SCHEMBL10933201 | 0.73 | NOTUM (1.00) | NOTUMKEAP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775762-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1988-10-04 | — | — | US | disclosed |