SCHEMBL10690143

SCHEMBL10690143

C#CCOc1cc(N2C(=O)C(C)=C(C)C2=O)c(F)cc1Cl

nearest known ligand 0.72

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPOX P50336 11/20 0.43
PGK1 P00558 1/20 0.39
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8684442 0.84 PPOX (0.43) PPOX
SCHEMBL314005 0.84 PPOX (0.51) PPOX
SCHEMBL29448833 0.84 PPOX (0.51) PPOX
SCHEMBL9872162 0.82 PGK1 (0.40) PPOXPGK1LMNA
SCHEMBL18470247 0.81 PGK1 (0.36) PPOXPGK1
SCHEMBL8686426 0.81 PPOX (0.39) PPOX
SCHEMBL9814305 0.81 PPOX (0.39) PPOXPGK1LMNA
SCHEMBL10448351 0.81 PPOX (0.43) PPOXPGK1
SCHEMBL9814304 0.79 PPOX (0.38) PPOXPGK1LMNA
SCHEMBL9577496 0.79 PPOX (0.38) PPOXPGK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0260228-A2 N-phenyl-malein imides and N-phenyl-succinimides with a herbicidal and a plant growth regulation activity CIBA-GEIGY AG (CH) 1988-03-16 EP disclosed