Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | PRKCA | P17252 | 3/20 | 0.45 |
| ▸ | HRAS | P01112 | 6/20 | 0.44 |
| ▸ | ESR1 | P03372 | 6/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.44 |
| ▸ | TOP1 | P11387 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10693709 | 1.00 | HDAC1 (0.51) | HDAC1HDAC2HDAC8PRKCAHRAS | |
| SCHEMBL1844965 | 1.00 | HDAC1 (0.51) | HDAC1HDAC2HDAC8PRKCAHRAS | |
| SCHEMBL26643297 | 0.92 | HDAC1 (0.50) | HDAC1HDAC2HDAC8PRKCAHRAS | |
| SCHEMBL1842219 | 0.92 | HDAC1 (0.48) | HDAC1HDAC2HDAC8PRKCAHRAS | |
| SCHEMBL1844640 | 0.92 | TMEM97 (0.46) | HDAC1HDAC2HDAC8KDM4EPOLB | |
| SCHEMBL1843769 | 0.91 | HDAC1 (0.47) | HDAC1HDAC2HDAC8PRKCAHRAS | |
| SCHEMBL1841707 | 0.91 | HDAC1 (0.49) | HDAC1HDAC2HDAC8PRKCAHRAS | |
| SCHEMBL2073218 | 0.91 | HDAC1 (0.63) | HDAC1HDAC2HDAC8PRKCAHRAS | |
| SCHEMBL1842154 | 0.91 | HDAC1 (0.48) | HDAC1HDAC2HDAC8PRKCAHRAS | |
| SCHEMBL26374814 | 0.90 | HRAS (0.47) | HDAC1HDAC2HDAC8PRKCAHRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766142-A | ANTICARCINOGENIC AGENTS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1988-08-23 | — | — | US | disclosed |