Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.63 |
| ▸ | EP300 | Q09472 | 4/20 | 0.49 |
| ▸ | PRKCA | P17252 | 3/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | HRAS | P01112 | 5/20 | 0.38 |
| ▸ | ESR1 | P03372 | 5/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.38 |
| ▸ | TOP1 | P11387 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26374313 | 0.94 | HDAC1 (0.54) | HDAC1HDAC2HDAC8EP300PRKCA | |
| SCHEMBL10693709 | 0.91 | HDAC1 (0.51) | HDAC1HDAC2HDAC8EP300PRKCA | |
| SCHEMBL1844965 | 0.91 | HDAC1 (0.51) | HDAC1HDAC2HDAC8EP300PRKCA | |
| SCHEMBL10690267 | 0.91 | HDAC1 (0.51) | HDAC1HDAC2HDAC8EP300PRKCA | |
| SCHEMBL12934349 | 0.86 | HDAC1 (0.68) | HDAC1HDAC2HDAC8EP300PRKCA | |
| SCHEMBL2071768 | 0.86 | HDAC1 (0.58) | HDAC1HDAC2HDAC8EP300PRKCA | |
| SCHEMBL1842219 | 0.86 | HDAC1 (0.48) | HDAC1HDAC2HDAC8EP300PRKCA | |
| SCHEMBL26374322 | 0.85 | HDAC1 (0.44) | HDAC1HDAC2HDAC8EP300ERBB2 | |
| SCHEMBL1843769 | 0.85 | HDAC1 (0.47) | HDAC1HDAC2HDAC8EP300PRKCA | |
| SCHEMBL1841707 | 0.85 | HDAC1 (0.49) | HDAC1HDAC2HDAC8EP300PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7863455-B2 | Electrochemically active ligand for sequence-specific detection of double-stranded nucleic acid molecule | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-01-04 | — | — | US | disclosed |
| US-20070172826-A1 | Electrochemically active ligand for sequence-specific detection of double-stranded nucleic acid molecule | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2007-07-26 | — | — | US | disclosed |
| EP-1719777-A1 | ELECTROCHEMICALLY ACTIVE LIGAND FOR SEQUENCE-SPECIFIC DETECTION OF DOUBLE-STRANDED NUCLEIC ACID MOLECULE | Japan Science and Technology Agency (JP) | 2006-11-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070172826-A1 | Electrochemically active ligand for sequence-specific detection of double-stranded nucleic acid molecule | POLRMT, POLM, POLI | HDAC1 2852/4885HDAC2 2783/4885HDAC8 1320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.