Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.39 |
| ▸ | STK4 | Q13043 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10370485 | 0.91 | MAP4K1 (0.42) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| Water SCHEMBL10689303 | 0.90 | MAP4K1 (0.41) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9129939 | 0.89 | KDM4E (0.61) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9748406 | 0.89 | KDM4E (0.61) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10692192 | 0.85 | LMNA (0.52) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9748487 | 0.84 | KDM4E (0.48) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9670973 | 0.84 | KDM4E (0.48) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10694404 | 0.82 | LMNA (0.45) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9669597 | 0.82 | LMNA (0.50) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10370861 | 0.81 | LMNA (0.43) | LMNAKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251308-A1 | 4-Quinolone-3-carboxylic-acid derivatives, process for their synthesis and pharmaceutical preparations containing them | Chemie Linz Gesellschaft m.b.H. (AT) | 1988-01-07 | — | — | EP | disclosed |