Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.43 |
| ▸ | TOP1 | P11387 | 5/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9129939 | 1.00 | KDM4E (0.61) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL9749739 | 0.92 | LMNA (0.60) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL9460824 | 0.91 | LMNA (0.49) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| Water SCHEMBL9784852 | 0.90 | LMNA (0.49) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL10690288 | 0.89 | LMNA (0.48) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL9748366 | 0.84 | LMNA (0.66) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL9749223 | 0.84 | LMNA (0.66) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL9748481 | 0.83 | KDM4E (0.63) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL9670968 | 0.83 | KDM4E (0.63) | KDM4ELMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL9750330 | 0.83 | KDM4E (0.46) | KDM4ELMNAALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091383-A | SUBSTITUTED BRIDGED DIAZABICYCLOALKYL QUINOLONE CARBOXYLIC ACIDS | PFIZER INC. (US) | 1992-02-25 | — | — | US | disclosed |