Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | HRH2 | P25021 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24791554 | 1.00 | LMNA (0.34) | LMNATSHRHSD11B1KDM4EMAPT | |
| SCHEMBL25128703 | 0.79 | — | — | |
| Iodide SCHEMBL11759002 | 0.76 | ALDH1A1 (0.40) | — | |
| SCHEMBL22591947 | 0.71 | — | — | |
| SCHEMBL18419999 | 0.71 | LMNA (0.34) | LMNATSHRHSD11B1KDM4EMAPT | |
| SCHEMBL18419943 | 0.71 | LMNA (0.34) | LMNATSHRHSD11B1KDM4EMAPT | |
| SCHEMBL3821667 | 0.71 | LMNA (0.34) | LMNATSHRHSD11B1KDM4EMAPT | |
| SCHEMBL18419965 | 0.71 | LMNA (0.34) | LMNATSHRHSD11B1KDM4EMAPT | |
| SCHEMBL2971736 | 0.71 | LMNA (0.34) | LMNATSHRHSD11B1KDM4EMAPT | |
| SCHEMBL17208563 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0283857-A1 | Benzylidenamino, benzylamino and benzoylamino imidazole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1988-09-28 | — | — | EP | disclosed |