Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10689343 | 0.77 | SMARCA2 (0.44) | MEN1KMT2ANPSR1TSHRALDH1A1 | |
| SCHEMBL10686710 | 0.74 | SIGMAR1 (0.57) | SIGMAR1MEN1KMT2AP2RX7BCHE | |
| SCHEMBL15475842 | 0.69 | CYP2A13 (0.42) | SIGMAR1MEN1KMT2AP2RX7CYP2A13 | |
| SCHEMBL10689968 | 0.69 | CYP1A2 (0.46) | SIGMAR1CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL15475839 | 0.68 | MEN1 (0.41) | SIGMAR1MEN1KMT2AP2RX7CYP2A13 | |
| Hydrochloric Acid SCHEMBL15475840 | 0.68 | MEN1 (0.41) | SIGMAR1MEN1KMT2AP2RX7CYP2A13 | |
| SCHEMBL28668332 | 0.64 | SMN1; SMN2 (0.52) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2094246 | 0.63 | CYP2A13 (0.66) | SIGMAR1MEN1KMT2ABCHEACHE | |
| SCHEMBL5318479 | 0.63 | MAPT (0.57) | SIGMAR1MEN1KMT2ANPSR1TSHR | |
| SCHEMBL11272304 | 0.63 | SIGMAR1 (0.45) | SIGMAR1MEN1KMT2AP2RX7NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732989-A | INTERMEDIATES FOR BACTERICIDES | G. D. SEARLE & CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4661602-A | ANTIANAEROBIC AGENTS | G. D. SEARLE & CO. (US) | 1987-04-28 | — | — | US | disclosed |