Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 11/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 4/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690580 | 0.86 | PDE2A (0.64) | AMY1APDE2APDE5APDE3BPDE3A | |
| SCHEMBL10689043 | 0.85 | PDE2A (0.47) | PDE2APDE5APDE3BPDE3AKDM4E | |
| SCHEMBL10691379 | 0.83 | PDE2A (0.46) | AMY1APDE2APDE5APDE3BPDE3A | |
| SCHEMBL10690472 | 0.83 | PDE2A (0.43) | AMY1APDE2APDE5APDE3BPDE3A | |
| SCHEMBL11356783 | 0.82 | PDE2A (0.50) | AMY1APDE2APDE5APDE3BPDE3A | |
| Hydrochloric Acid SCHEMBL11238238 | 0.81 | PDE2A (0.49) | AMY1APDE2APDE5APDE3BPDE3A | |
| SCHEMBL10690513 | 0.80 | AMY1A (0.47) | AMY1APDE2APDE5APDE3BPDE3A | |
| Water SCHEMBL10869421 | 0.80 | PDE2A (0.47) | AMY1APDE2APDE5APDE3BPDE3A | |
| Water SCHEMBL10868986 | 0.80 | PDE2A (0.47) | AMY1APDE2APDE5APDE3BPDE3A | |
| SCHEMBL10610362 | 0.79 | PDE2A (0.50) | PDE2APDE5APDE3BPDE3AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4722929-A | Novel 2-phenyl-imidazoles and pharmaceutical compositions containing same | DR. KARL THOMAE GMBH (DE) | 1988-02-02 | — | — | US | disclosed |
| EP-0149200-A1 | Novel 2-pnenyl-imidazoles, their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1985-07-24 | — | — | EP | disclosed |