SCHEMBL10690529

SCHEMBL10690529

CC(Oc1ccc(Sc2ncc(C(F)(F)F)cc2Cl)cc1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.53
MEN1 O00255 3/20 0.53
L3MBTL1 Q9Y468 1/20 0.49
PKM P14618 3/20 0.47
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46
MAPK1 P28482 1/20 0.45
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
PPARD Q03181 1/20 0.44
PPARA Q07869 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
LIPE Q05469 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10694737 0.88 MEN1 (0.52) KMT2AMEN1L3MBTL1PKMCYP1A2
SCHEMBL10694742 0.85 MEN1 (0.45) KMT2AMEN1L3MBTL1PKMCYP1A2
Haloxyfop SCHEMBL29792114 0.81 SMN1; SMN2 (0.65) KMT2AMEN1L3MBTL1ALDH1A1SMN1; SMN2
Haloxyfop SCHEMBL29426466 0.81 SMN1; SMN2 (0.65) KMT2AMEN1L3MBTL1ALDH1A1SMN1; SMN2
Haloxyfop-R-Methyl SCHEMBL29730427 0.81 SMN1; SMN2 (0.65) KMT2AMEN1L3MBTL1ALDH1A1SMN1; SMN2
Haloxyfop SCHEMBL33627 0.81 SMN1; SMN2 (0.65) KMT2AMEN1L3MBTL1ALDH1A1SMN1; SMN2
Haloxyfop SCHEMBL3675562 0.81 SMN1; SMN2 (0.65) KMT2AMEN1L3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL10948498 0.81 PPARA (0.46) KMT2AMEN1PKMCYP1A2CYP2C19
Haloxyfop-R-Methyl SCHEMBL119996 0.81 SMN1; SMN2 (0.65) KMT2AMEN1L3MBTL1ALDH1A1SMN1; SMN2
Haloxyfop SCHEMBL1560810 0.81 SMN1; SMN2 (0.65) KMT2AMEN1L3MBTL1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0000483-B1 TRIFLUOROMETHYL PYRIDINYL(OXY/THIO)PHENOXY PROPANOIC ACIDS AND PROPANOLS AND DERIVATIVES THEREOF THE DOW CHEMICAL COMPANY (US) 1981-10-14 EP claimed
US-4753673-A GRASSY WEEDS THE DOW CHEMICAL COMPANY (US) 1988-06-28 US disclosed
US-4628099-A INTERMEDIATES FOR HERBICIDES THE DOW CHEMICAL COMPANY (US) 1986-12-09 US disclosed
US-4551170-A Herbicidal trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanols and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1985-11-05 US disclosed
US-4523017-A REACTING CHLORIDE SUBSTITUTED PYRIDINE COMPOUND WITH SUBSTITUTED PHENOL COMPOUND THE DOW CHEMICAL COMPANY (US) 1985-06-11 US disclosed
US-4522647-A Substituted phenoxyalkanediones and their herbicidal method of use ZOECON CORPORATION (US) 1985-06-11 US disclosed
US-4497965-A PRE-AND POSTEMERGENT HERBICIDES ZOECON CORPORATION (US) 1985-02-05 US disclosed
US-4491468-A Herbicidal trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanenitriles and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1985-01-01 US disclosed
US-4479001-A Trifluoromethyl pyridinylthiophenoxy propanoic acids and propanols and derivatives thereof THE DOW CHEMICAL COMPANY (US) 1984-10-23 US disclosed
EP-0109483-A1 Substituted phenoxyalkane diones, intermediates for these compounds and the use of phenoxyalkane diones in the control of weeds ZOECON CORPORATION (US) 1984-05-30 EP disclosed
US-4448966-A HERBICIDES ZOECON CORPORATION (US) 1984-05-15 US disclosed
EP-0057473-A2 A process for preparing trifluoromethylpyridyl (oxy/thio) phenoxypropionic compounds being especially active as herbicides THE DOW CHEMICAL COMPANY (US) 1982-08-11 EP disclosed
EP-0000483-B1 TRIFLUOROMETHYL PYRIDINYL(OXY/THIO)PHENOXY PROPANOIC ACIDS AND PROPANOLS AND DERIVATIVES THEREOF THE DOW CHEMICAL COMPANY (US) 1981-10-14 EP disclosed