Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690529 | 0.88 | KMT2A (0.53) | MEN1KMT2AMAPK1CYP1A2CYP2C19 | |
| SCHEMBL731273 | 0.82 | L3MBTL1 (0.62) | MEN1KMT2AHPGDL3MBTL1ALDH1A1 | |
| SCHEMBL11262145 | 0.82 | IDH1 (0.46) | MEN1KMT2ACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL11280124 | 0.82 | POLB (0.53) | MEN1KMT2AHPGDL3MBTL1POLB | |
| SCHEMBL10694742 | 0.81 | MEN1 (0.45) | MEN1KMT2AMAPK1CYP1A2CYP2C19 | |
| SCHEMBL11514005 | 0.81 | IDH1 (0.46) | MEN1KMT2ACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL11516273 | 0.80 | IDH1 (0.53) | KMT2AL3MBTL1NPSR1POLB | |
| SCHEMBL11516087 | 0.80 | IDH1 (0.48) | MEN1KMT2AL3MBTL1ALDH1A1POLB | |
| SCHEMBL11512650 | 0.78 | KMT2A (0.49) | MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL10644918 | 0.77 | SMN1; SMN2 (0.53) | MEN1KMT2AMAPK1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4753673-A | GRASSY WEEDS | THE DOW CHEMICAL COMPANY (US) | 1988-06-28 | — | — | US | disclosed |
| US-4628099-A | INTERMEDIATES FOR HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1986-12-09 | — | — | US | disclosed |
| US-4551170-A | Herbicidal trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanols and derivatives thereof | THE DOW CHEMICAL COMPANY (US) | 1985-11-05 | — | — | US | disclosed |
| US-4523017-A | REACTING CHLORIDE SUBSTITUTED PYRIDINE COMPOUND WITH SUBSTITUTED PHENOL COMPOUND | THE DOW CHEMICAL COMPANY (US) | 1985-06-11 | — | — | US | disclosed |
| US-4491468-A | Herbicidal trifluoromethyl pyridinyloxyphenoxy and pyridinylthiophenoxy propanenitriles and derivatives thereof | THE DOW CHEMICAL COMPANY (US) | 1985-01-01 | — | — | US | disclosed |
| US-4479001-A | Trifluoromethyl pyridinylthiophenoxy propanoic acids and propanols and derivatives thereof | THE DOW CHEMICAL COMPANY (US) | 1984-10-23 | — | — | US | disclosed |